It is used to control a wide variety of pests. How the information is presented. SC […] [8] Its labeled use rate is set at 1 ppm (1 mg a.i./kg of grain) and its maximum residue limit (MRL) or tolerance is set at 1.5 ppm. Spinosad is a mixture of chemical compounds in the spinosyn family that has a generalized structure consisting of a unique tetracyclic ring system attached to an amino sugar (D-forosamine) and a neutral sugar (tri-Ο-methyl-L-rhamnose). It is considered a natural product, thus is approved for use in organic agriculture by numerous nations. Look for spinosad under the following trade names: Monterey Garden Insect SprayR, Ferti-lomeR Borer, Bagworm, Leafminer & Tent Caterpillar Spray, and Bulls-EyeTM Bioinsecticide. CAS number: 168316-95-8 . Conserve SC Spinosad/spintor Spinosyn A and Spinosyn D 5 Dow AgroSciences Coragen Chlorantraniliprole 3-bromo-N-[4-chloro-2-methyl-6-[(methylamino)carbonyl]phenyl]-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxamide 28 Dupont Co-Ral Coumaphos O,O-diethyl O-(3-chloro-4-methyl-2-oxo2H-1-enzopyuran 7-yl- phosphorothioate 1B Bayer Corporation These include thrips, leafminers, spider mites, mosquitoes, ants, fruit flies and others.Many products containing spinosad are used on crops and ornamental plants. It was first registered as a pesticide in the United States for use on crops in 1997. [11][12][13], Spinosyn A does not appear to interact directly with known insecticidal-relevant target sites, but rather acts via a novel mechanism. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. [3], Spinosad is a novel mode-of-action insecticide derived from a family of natural products obtained by fermentation of S. spinosa. It is a mixture of two chemicals called spinosyn A and spinosyn D. It is used to control a wide variety of pests. Min.Order: 1 Kilogram FOB Price: USD $ 1.0-3.0/Kilogram hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm US Brand Name. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The genus Saccharopolyspora was discovered in 1985 in isolates from crushed sugarcane. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Tradename (spinosad) Suspension, 0.9% was demonstrated to be statistically superior to an active comparator NIX (permethrin 1%) in each of two well-controlled pivotal, Phase 3 trials. Attracts and kills insects feeding on or near the base of plants. Some of these products are approved for use in organic agriculture. Available for Android and iOS devices. Product-type: PT18. Spinosad topical suspension, 0.9%, was approved by the U.S. Food and Drug Administration (FDA) on 2011-01-18 for the topical treatment of head lice infestation in patients four (4) years of age and older. Spinosad is a mixture of spinosyn A and spinosyn D. Chemical name ... Trade names: Success, Tracer, Spintor, Spinoace, Boomerang, Laser, Extinosad Structural formula: Spinosyn A O O O O O H H H H H CH 3 O CH 3 O CH CH 3O 3 OCH 3 CH 3 2 (CH 3) 2N OCH 3. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Known as a developmental or reproductive toxin in humans, this chemical is highly toxic to aquatic life. Substance name: Spinosad. Fire Ants, spider mites, and reproductive toxins… Spinosoid binding leads to disruption of acetylcholine neurotransmission. Because spinosad is a relatively new compound, it's not yet found its way onto many garden store shelves. Spread the knowledgeHi all, I have collected a list of all the major insecticides available in the market and arranged them in a learn-able organized tabular form. Common, Chemical and Trade Names of Insecticides Used in this Guide Trade Common Name Chemical Name IRAC Classification Company Abate Temephos O,O -(thiodi-4,1-phenylene) O,O, O' O'-tetramethyl phosphorothioate 1B BASF Corporation Abba Abamectin a mixture of avermectin B1a (10E,14E,16E,22Z)- It works by causing nervous system excitation in insects. Bio-insecticides: A. Spinosad has been used around the world for the control of a variety of insect pests, including Lepidoptera, Diptera, Thysanoptera, Coleoptera, Orthoptera, and Hymenoptera, and many others. Comfortis and Trifexis brands treat adult fleas on pets; the latter also prevents heartworm disease. Spinosad 45% SC is a natural substance made by a soil bacterium that can be toxic to insects. [1], Spinosad is highly active, by both contact and ingestion, in numerous insect species. supplier Spinosad 168316-95-8. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. It is marketed as the trade name Natroba in the US by ParaPRO Pharmaceuticals. Spinosad's widespread commercial launch was deferred, awaiting final MRL or tolerance approvals in a few remaining grain-importing countries. [8] It was first registered as a pesticide in the United States for use on crops in 1997. Pyriproxyfen has low acute toxicity. This drug has forty-eight patent family members in thirty countries. IUPAC name: Spinosad as a mixture of 50-95 % spinosyn A and 5-50 % spinosyn D. EC number:-; 434-300-1 . Spinosad is a macrocyclic lactone and therefore should in theory be contraindicated for use on dogs with the MDR-1 mutation (see Chapter 5: Vulnerable Patients). Spinosad, comprising spinosyn A and spinosyn D in a ratio of approximately 85:15, is the active ingredient in the formulations TRACER and LASER. [15] Similarly, administration of 25 mg/kg/day to rats for 24 months did not result in tumor formation. [5] Its overall protective effect varies with insect species and life stage. [5] Two other uses for spinosad are for pets and humans. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Spinosad is an insecticide based on chemical compounds found in the bacterial species Saccharopolyspora spinosa. [2] Spinosad so far has proven not to cause cross-resistance to any other known insecticide. In the US, pyriproxyfen is often marketed under the trade name Nylar. Drug class (es): topical anti-infectives. We comply with the HONcode standard for trustworthy health information -, Search the entire Drugs.com site for spinosad. Important: The information below refers to products available in the United States that contain spinosad. TRACER is an suspension concentrate formulation with 480 g ai.L-1, while LASER is an aqueous suspension emulsion in oil with 125 g ai.L-1. [7] The apparent lack of spinosyn A metabolism may contribute to its high level of activity, and may compensate for the slow rate of penetration. Natroba; Descriptions. [6] The spinosyns and spinosoids have a novel mode of action, primarily targeting binding sites on nicotinic acetylcholine receptors (nAChRs) of the insect nervous system that are distinct from those at which other insecticides have their activity. 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